PRF - 110

PRF-110 is a viscous clear oil-based solution that is instilled (deposited) directly into the surgical wound, and spreadable over the complete wound surface, to provide localized and extended post-operative analgesia. Its physical characteristics and composition are key to it being well-tolerated and its ease of use:

  • PRF-110 is highly viscous and thus stays in place when placed into a surgical wound bed.
  • PRF-110 remains within the surgical site when the skin is closed, without being toxic or proinflammatory.
  • PRF-110 is easy to administer and its use is consistent with current surgical practice.
  • PRF-110 is highly uniform and resistant to degradation in the wound, resulting is sustained/extended release of the analgesic.
  • Ropivacaine, the active drug used in PRF-110, is a safe and well characterized local anesthetic.
  • The components that make up the remainder of the PRF-110 formulation are classified as GRAS (Generally Regarded as Safe) by the FDA.

Pain Reduction Time

Studies have shown 48 hours of pain reduction in healthy volunteers and up to 72 hours in a clinical setting

Scalable and Cost Effective

Low variable costs allows for ease of manufacturing and production to meet high market demand

Easy Application

Avoiding multiple injection reduces delivery time and complexity, optimizes efficacy and reduces the risk of hematoma

Core Platform

Platform can be utilized for a wide range of APIs to generate sustainable pipeline of new product applications